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DRY EYE

SYNDROME
      WHAT OUR TEARS ARE SAYING

Dby Cory Collier, MD                                                    “Dry eye syndrome is
             ry eye syndrome (DES) affects up to 30 percent of the                   a common condition
             population over the age of 50. DES can be a chronic                     leading to significant
             and in some cases debilitating condition impacting our                     physical and visual
             comfort, vision and quality of life.                         ”discomfort for many
   DES typically presents with symptoms of dryness, burning,                                           people.
tearing, blurry vision, fluctuating vision, or a sandy or gritty
sensation in the eyes. Some patients may have no symptoms at all     quantity, observation of oil glands located along the eyelid as well
or may incorrectly attribute these symptoms to other conditions      as topical dyes that allow for the assessment of inflammation and
affecting their eyes.                                                irritation on the surface of the eye.

   Age is a major risk factor for DES. Females are more commonly        These tests help distinguish the two major forms of DES;
affected than males especially those women on hormone                aqueous deficient and evaporative dry eye. In aqueous deficient
replacement therapy. Additional risk factors include low humidity    dry eye, the production of the water layer of tears is generally low
environments, prolonged reading or computer use, and poor dietary    resulting in minimal tears. In some individuals the eye responds
habits.                                                              to an initial lack of tears by attempting to over compensate with
                                                                     excessive tear production. Unfortunately these tears are of poor
   At the center of any discussion on DES are tears. Tears are       quality and generally full of inflammatory molecules that do little
made of three primary layers including an outer lipid or oil layer,  to address the underlying deficiency. In contrast, evaporative dry
a middle aqueous or water layer and a layer of sugary proteins       eye is centered on poor production or composition of the oil layer.
known as mucins. In reality these components exist in a much         The oil layer helps maintain tears on the eye by preventing their
more dynamic and continuously mixing environment than the            premature evaporation. With an imbalance in the oil layer, tears
layer model suggests.                                                evaporate from the eyes quickly. Clinically many patients exhibit
                                                                     signs of both forms of dry eye.
   The diagnosis of DES is made after consideration of patient
symptoms and a thorough eye examination. Diagnostic tools               The treatment of DES varies depending on the type and severity
include symptom questionnaires, assessments of tear quality and      of DES. Tear supplementation with artificial tears is a staple in the
                                                                     management of DES.Other first-line options include oral Omega-3
                                                                     supplements, warm eyelid compresses and eyelid cleansers. In more
                                                                     advanced cases, prescription medications including Restasis TM,
                                                                     other topical anti-inflammatories and oral medications may be
                                                                     employed. Punctal occlusion, a process by which the tear drainage
                                                                     system is closed to allow for the accumulation of our own tears, is
                                                                     often performed when topical therapies fail to provide relieve.

                                                                        Dry eye syndrome is a common condition leading to
                                                                     significant physical and visual discomfort for many people. If you
                                                                     are experiencing symptoms, talk to your eye care provider for an
                                                                     individualized treatment approach.

	20 										                                                       Life in Naples | December 2015
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