Page 70 - LIN March-2023 50-84-sent
P. 70

Technically Speaking


















                                  that old devil sun
                                                                                  sun






        by Dave Trecker
                   e’re called the Sunshine State for a reason. We have,   are easily formulated into oils and salves, but their small size eases
        W                                                          absorption through the skin. One big plus, one big minus.
        W
                   on average, 237 sunny days a year, 266 in Southwest
                   Florida. The five sunniest cities are Bonita Springs,
                                                                      A recent article in Chemical & Engineering News frames the
        Ft. Myers Beach, Marco Island, Naples and Punta Gorda.     dilemma. Unlike most of the rest of the world, the United States
           That’s one of the reasons people move here. Why put up with   treats sunscreens like over-the-counter medicines. Their approval
        the gloomy Northeast or the cloudy, cold Midwest if you can live   requires testing to show they are GRAS, “generally regarded
        in sunny Florida?                                          as safe.” Because of the risk of bodily absorption, the tests can
           But there’s a downside. That bright, warming sun causes skin   take years and cost tens of millions of dollars – not much for an
        cancer. Solar ultraviolet radiation is responsible for 10,000 deaths   expensive drug, but a killer for a cheap sunblock.
        a year in the United States, a number that has been increasing at   Putting the final nail in the coffin, scientists recently published
        an alarming rate.                                          a study showing that commonly used organic UV filters often
           How can that be, you ask? We have the best technology in   “turn up in the bloodstream at levels that trigger a toxicology study
        the world. We have super computers that can solve any problem.   requirement.” That isn’t to say they’re dangerous. But they must be
        We can guide missiles to a pinpoint target, develop life-saving   tested. That applies to some 15 existing sunblocks and a backlog of
        vaccines, explore outer space. Surely we can soak up UV rays.  six to seven new ones.
           And we can, of course. We have a whole bunch of sunscreens   The situation is far different overseas. Most of the rest of the
        to do just that, products widely available at CVS and Walgreens.   world treats sunblocks as cosmetics, comfortable that the small
        It’s not like we have to go unprotected. Pick up some sunblock   organics have been used for decades without serious problems.
        and slather it on.                                            So where do we go from here? Help may be on the way.
        So what's the problem?                                        A triazole derivative discovered 20 years ago has been
        So w
                                   em?
                       he pr
                               obl
               hat's t
                                                                   resurrected and exhaustively examined. Called bemotrizinol, it
           The problem is medical studies show that many of the most
                                                                   seems to meet all of the requirements. It’s a big molecule. It soaks
        widely used sunblocks are absorbed into the bloodstream.
                                                                   up a wide band of UV light. It’s stable, easily formulated and clear
        Without data to prove that no harm results, the FDA is poised
                                                                   when applied. Little, if any, passes into the bloodstream, and the
        to yank approval of these chemicals. Pull them off of the shelves.
                                                                   toxicology looks great.
        And no new products can be added to the mix without extensive
                                                                      A company called DSM recently completed testing of
        testing.
                                                                   bemotrizinol and plans to submit the data to the FDA by
                                         g ab
                                       in
                                                         e?
                                                  t her
                                               ou
        Just w
                          e we t
        Just what are we talking about here?                       mid-2023. Rapid approval is expected.
                                  alk
                 hat ar
           Sunscreens work in several ways.
                                                                   What should we do in the meantime?
                                                                   W  hat should we do in t       he m   eantim   e?
           Inorganics like titanium dioxide and zinc oxide simply reflect
                                                                      Experts say to plaster on the titanium dioxide or zinc oxide.
        the UV rays. They are not absorbed through the skin, a big plus.
                                                                   Looking like a kabuki warrior isn’t such a bad thing.
        But they are paint pigments. They make you look like a kabuki
        warrior, a big minus for most.
                                                                   About the Author
           Organic sunscreens function differently. They soak up the light   Ab ou t t he Au t hor
        energy and transfer it to thermal energy, blunting the threat of   Dr. Trecker is a chemist and retired Pfizer executive living
        sunburn. Oxybenzone, octinoxate, avobenzone, homosalate and   in Naples.
        others operate this way. Because they are small molecules, they
     70                                                                                                      Life in Naples | March 2023
   65   66   67   68   69   70   71   72   73   74   75